Written Authority Required Drugs

Breast cancer - metastatic breast cancer

The PBS subsidises lapatinib, pertuzumab, trastuzumab and trastuzumab emtansine for patients with metastatic breast cancer.

 Patient eligibility

Treatment with lapatinib, pertuzumab, trastuzumab subcutaneous (s.c) and intravenous (i.v.) and trastuzumab emtansine can be subsidised through the Pharmaceutical Benefits Scheme (PBS) under the National Health Act 1953, Section 85 and Section 100 for a patient with human epidermal growth factor receptor 2 (HER2) positive metastatic breast cancer.

Patients must be eligible for the PBS and meet the relevant restriction criteria.

The Schedule of Pharmaceutical Benefits outlines the restrictions for prescribing lapatinib, pertuzumab, trastuzumab and trastuzumab emtansine.

Section 100 arrangements

This item is available to a patient who is attending:

  • an approved private hospital
  • a public participating hospital, or
  • a public hospital

and is either a

  • day admitted patient
  • non-admitted patient, or
  • patient on discharge

These items aren’t available as a PBS benefit for hospital in-patients. You need to include the hospital name and provider number on the authority application form.


Initial treatment

Make all initial applications for authority approval to prescribe lapatinib, pertuzumab, trastuzumab and trastuzumab emtansine for the treatment of HER2-positive metastatic breast cancer in writing and:

All applications must include the completed:

Continuing, changing or recommencing treatment

To make continuing applications for treatment with pertuzumab, trastuzumab and trastuzumab emtansine call the PBS Complex Drugs Programs enquiry line.

Continuing treatment with lapatinib is Authority Required (Streamlined) and does not require prior authority approval from the Department of Human Services.

Further information

Call the PBS Complex Drugs Programs enquiry line for more information.

This information was printed Wednesday 22 May 2019 from https://www.humanservices.gov.au/organisations/health-professionals/services/medicare/written-authority-required-drugs/drug-program-or-condition/breast-cancer-metastatic-breast-cancer It may not include all of the relevant information on this topic. Please consider any relevant site notices at https://www.humanservices.gov.au/individuals/site-notices when using this material.

Page last updated: 22 February 2019